Decide whether immediate treatment is necessary or confidently opt for active surveillance. The breast cancer has a high risk of local recurrence, and absolute benefit of radiation therapy is likely to be greater. This test needs further study and is not yet part of standard practice. Making cancer care smarter. Overview What is Genomic Testing? The Oncotype DX score is low If the test shows a low risk of metastasis the Oncotype DX score is low , the use of hormone therapy alone may be considered [ ]. The Medicare program and several other major insurance companies have agreed to cover the Oncotype DX test.